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David M. Harlan, MD

Co-Director, Diabetes Center of Excellence and The William and Doris Krupp Professor of Medicine at UMass Chan Medical School

Director, Breakthrough T1D Barbara Dewey Cammett Center of Excellence in New England 

Diabetes Care

While chief of the Diabetes Division at UMass Memorial, Dr. Harlan increased volume and significantly improved the level of care in the adult diabetes clinic. He leads by example and strives to improve care delivery systems. Dr. Harlan's patients benefited from his extensive knowledge of the disease and his ability to listen to each individual and work with them to develop a diabetes management plan. He believes that the person living with diabetes is the most critical member of their care team.

Type 1 Diabetes Research

Over the past 40 years as a physician-scientist, Dr. Harlan has led basic and clinical research exploring the pathophysiology of diabetes. His current clinical studies are testing new therapies and investigating human biology related to diabetes and its treatment. Specifically, genetically modifying stem cell-derived pancreatic islets that can be transplanted into people with type 1 diabetes, without the need for immunosuppressant drugs.

Dr. David Harlan, MD, Breakthrough T1D Center of Excellence in New England Director

In the News

JDRF Appoints Dr. David Harlan to Lead a New England Research Collaboration

David Harlan, MD Spectrum News JDRF

Dr. Harlan's professional passion became personal when his son was diagnosed with Type 1 diabetes, as mentioned in this Spectrum News coverage of the JDRF (now Breakthrough T1D) appointing him as Director of their New England Center of Excellence. 

Additional News Coverage 

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Rachmiel Levine Award | City of Hope Levine-Riggs Diabetes Research Symposium

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Dr. Harlan was recognized for his diabetes research career.  In this video he shares his award lecture with colleagues at Worcester's UMass Memorial Medical Center

HLA Class II antigen processing and presentation pathway components demonstrated by transcriptome and protein analyses of beta cells from donors with type 1 diabetes

We resolved a three-decades-long debate by definitively showing that beta cells express these important immune pathway gene products

T1D Pathogenesis: Lessons Learned & Forgotten and Open Questions

 David Harlan, MD - Insulin's 100th Birthday

This talk highlights progress made in diabetes treatments, comparing old vs. new ideas, and challenges common assumptions & dogmas about Type 1 diabetes