Our mission is to understand how conformational changes and internal dynamics affect protein function and mechanism of action.  

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The focus of my laboratory is to understand the relationship between the structure, stability, and dynamics of proteins. In particular we investigate how the structure and dynamics of a protein affect molecular recognition, binding specificity, allostery and stability. To this end, we take a multi-disciplinary approach combining the strengths of biophysical, biochemical and in vivo techniques, with particular emphasis on solution NMR spectroscopic and computational methods.  

Research Areas

Commonly-Used Techniques

We utilize biophysical, biochemical, and in vivo techniques with a particular emphasis on NMR spectroscopy and computational methods.