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Step 1 Content | Microbiology

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General Microbiology & Infectious Disease Topics

  • Microbial classification and its basis
  • Bacteria: structure, metabolism, genetics, virulence factors, pathogenesis
  • Viruses: replication, genetics, latent/persistent infections, oncogenic viruses
  • Fungi: structure, physiology, pathogenesis, epidemiology
  • Parasites: structure, laboratory diagnosis, pathogenesis
  • Principles of sterilization and pure culture techniques
  • Mechanisms of action and resistance of antimicrobials (antibacterials, antivirals, antifungals, antiparasitic)

System-Specific Microbiology & Infectious Diseases

System

Infectious Diseases

Hematopoietic & Lymphoreticular

Infections of the blood, lymphatics, and reticuloendothelial system (HIV, EBV, malaria)

Central & Peripheral Nervous

Meningitis (bacterial, viral, fungal, parasitic), encephalitis, abscess, prion diseases

Skin & Connective Tissue

Bacterial (impetigo, cellulitis, necrotizing fasciitis), viral (herpes, varicella, rubella), fungal (tinea, candidiasis), parasitic (scabies, lice)

Musculoskeletal

Osteomyelitis (Staphylococcus aureus, TB), septic arthritis (gonococcal, non-gonococcal), Lyme disease

Respiratory

Upper respiratory infections (sinusitis, pharyngitis), lower respiratory infections (pneumonia, bronchiectasis, TB, endemic fungal infections)

Cardiovascular

Endocarditis (bacterial, fungal), myocarditis (viral, parasitic, bacterial), pericarditis

Gastrointestinal

Hepatitis (A, B, C, D, E), Helicobacter pylori (peptic ulcer), food poisoning (Salmonella, Shigella, E. coli), parasitic infections

Renal/Urinary

Urinary tract infections (E. coli, Proteus, Klebsiella), pyelonephritis, schistosomiasis

Reproductive

Sexually transmitted infections (syphilis, gonorrhea, chlamydia, HPV, herpes, trichomoniasis)

Endocrine

Infectious endocrinopathies (mumps → orchitis, TB of adrenal glands)


 

MAR 2025