Cell Biology of the Viral and Retroviral Life Cycle

Selected publications

For a complete list, see: https://orcid.org/0000-0002-1069-1816

Luban J, Sattler RA, Mühlberger E, Graci JD, Cao L, Weetall M, et al. The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines. Virus Res [Internet]. 2021; 292:198246. Available from: http://dx.doi.org/10.1016/j.virusres.2020.198246.
  
Kim K, Dauphin A, Komurlu S, McCauley SM, Yurkovetskiy L, Carbone C, et al. Cyclophilin A protects HIV-1 from restriction by human TRIM5α. Nat Microbiol [Internet]. 2019; 4(12):2044–51. Available from: http://dx.doi.org/10.1038/s41564-019-0592-5.
  
Xu H, Franks T, Gibson G, Huber K, Rahm N, Strambio De Castillia C, et al. Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay. Retrovirology [Internet]. 2013; 10:70. Available from: http://dx.doi.org/10.1186/1742-4690-10-70.
  
Pertel T, Hausmann S, Morger D, Züger S, Guerra J, Lascano J, et al. TRIM5 is an innate immune sensor for the retrovirus capsid lattice. Nature [Internet]. 2011; 472(7343):361–5. Available from: http://dx.doi.org/10.1038/nature09976.
  
Sokolskaja E, Olivari S, Zufferey M, Strambio-De-Castillia C, Pizzato M, Luban J. Cyclosporine blocks incorporation of HIV-1 envelope glycoprotein into virions. J Virol [Internet]. 2010; 84(9):4851–5. Available from: https://doi.org/10.1128/jvi.01699-09.
  
Neagu MR, Ziegler P, Pertel T, Strambio-De-Castillia C, Grütter C, Martinetti G, et al. Potent inhibition of HIV-1 by TRIM5-cyclophilin fusion proteins engineered from human components. J Clin Invest [Internet]. 2009; 119(10):3035–47. Available from: https://doi.org/10.1172/JCI39354.
  
Sebastian S, Grütter C, Strambio-De-Castillia C, Pertel T, Olivari S, Grütter MG, et al. An invariant surface patch on the TRIM5alpha PRYSPRY domain is required for retroviral restriction but dispensable for capsid binding. J Virol [Internet]. 2009; 83(7):3365–73. Available from: https://doi.org/10.1128/jvi.00432-08

Strambio-De-Castillia C, Hunter E. Mutational analysis of the major homology region of Mason-Pfizer monkey virus by use of saturation mutagenesis. J Virol. American Society for Microbiology (ASM); 1992; 66(12):7021–32. Available from: https://doi.org/10.1128/jvi.01699-09