Wernicke-Korsakoff disease

A disease produced by thiamine deficiency (most often in patients with long-standing chronic alcoholism). Symptoms include ocular abnormalities (nystagmus, conjugate gaze paralysis), ataxia, and global confusion, all of which may be corrected by giving thiamine. However survivors may be left with an enduring defect in learning and memory (this is the Korsakoff component). Compare with Korsakoff's "psychosis".