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Fiachra Humphries, PhD

Research Focus - Defining How Innate Immune Shapes the Tumor Microenvironment

  • The role of type I IFN in the tumor microenvironment
  • Regulation of tumor associated macrophages
  • Regulation of tumor cell pyroptosis
  • Regulation of tumor cell ferroptosis
  • Plasma membrane rupture in tumor cells 

Representative Publication

Jiang Y, Yang Y, Hu Y, et al. Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade. Cell Rep. 2022;41(4):111553. 

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