Job Dekker, PhD
Research Focus - Mechanisms of Chromosome Folding
- Determining the pathways by which cells build mitotic chromosomes and segregate sister chromatids
- Elucidating the molecular mechanisms by which cells fold their genomes during the cell cycle
- Mapping how genomic rearrangements in cancer cells rewire enhancer-promoter interactions
- Analyzing the impact of nuclear organization on DNA damage repair outcomes
Representative Publication
Dixon JR, Xu J, Dileep V, et al. Integrative detection and analysis of structural variation in cancer genomes. Nature Genet. 2018;50(10):1388–1398.