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Kate Fitzgerald, PhD

Research Focus - Leveraging Nucleic Acid Sensing Pathways for Cancer Immunotherapy

  • Understanding inflammatory responses and colonic cancer
  • Elucidating tumor DNA-driven responses
  • Characterizing the cGAS (cyclic GMP-AMP synthase)-STING (stimulator of interferon genes) signaling pathway and anti-tumor immunity 

Representative Publication

Motwani M, Pesiridis S, Fitzgerald KA. DNA sensing by the cGAS-STING pathway in health and disease. Nat Rev Genet. 2019;20(11):657-674.

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