Prabhani U. Atukorale, PhD
Research Focus - Engineering Immunomodulatory Nanomaterials Technologies for Reprogramming Tumor Microenvironment Immunity
- Design of nanomaterials that serve as drug carriers for multiple synergistic innate immune agonists
- Development of novel cancer vaccination strategies
- Reprogramming of immunity in difficult-to-treat cancers, including metastasis
- Improvement of efficacy of current clinical cancer immunotherapies, such as checkpoint inhibitors and CAR T cells, by combination with novel immunomodulatory nanoparticles
Representative Publication
Atukorale PU, Raghunathan SP, Raguveer V, et al. Nanoparticle encapsulation of synergistic immune agonists enables systemic codelivery to tumor sites and IFNβ-driven antitumor immunity. Cancer Res. 2019;79(20):5394-5406.