Sharon Cantor, PhD
Research Focus - Defining Replication Stress and Therapy Response Outcomes Regulated by the Fanconi Anemia/BRCA Pathway
- Characterizing replication stress responses mediated by the Fanconi Anemia/BRCA pathway
- Defining pathogenic mutations in hereditary breast/ovarian cancer genes
- Defining and targeting replication stress suppression pathways in cancer
- Understanding the mechanisms of therapy response and resistance in cancer
Representative Publication
Cong, K, Peng, M, Koushelt, AN, et al. Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency. Mol Cell. 2021;81(15):3128-3144.e7.