Wen Xue, PhD
Research Focus - CRISPR-based Liver Cancer Modeling and Gene Therapy
- Engineering CRISPR-based mouse models of cancer
- Identifying a new tumor suppressor gene network in liver cancer
- Targeting KRAS in lung cancer therapy using small RNA tools
- Developing and optimizing new CRISPR tools for genome editing
- Correcting disease genes in vivo using CRISPR genome editing
Representative Publication
Liu P, Liang S-Q, Zheng C, et al. Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice. Nat Commun. 2021;12(1):2121