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“This is an exciting time to be pursuing a career in medicine and applying to UMass Chan Medical School.”
Photo of Dean Flotte

About the dean

Terence R. Flotte, MD, is provost, dean and executive deputy chancellor of UMass Chan Medical School, the only public medical school in Massachusetts. Since joining UMass Chan in 2007, Dr. Flotte has forged a path of unprecedented growth and achievement for the research, education and academic missions of the campus. An internationally known scientist, Flotte has conducted research on cutting edge molecular therapeutics that led to the first successful gene transfer with adeno-associated virus (AAV) in animals and the first ever human trial of an AAV. He also led the first human recombinant AAV trials in alpha-1 antitrypsin deficiency and Tay-Sachs disease, with the latter showing promising clinical benefits. He is the author of more than 280 scholarly papers and his research has been funded by the National Institutes of Health and the Alpha One Foundation. Since 2015, Flotte has also been editor-in-chief of gene therapy’s oldest journal family, Human Gene Therapy. 

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News articles

  • Faculty achievements recognized at UMass Chan’s Educational Recognition Awards and Last Lecture

    Faculty achievements recognized at UMass Chan’s Educational Recognition Awards and Last Lecture

    Howard J. Sachs, MD, associate professor of medicine, delivered the Last Lecture titled “The Inevitable Journey.”

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  • UMass Chan Medical School partners on national effort to advance nutrition education in medicine

    UMass Chan Medical School partners on national effort to advance nutrition education in medicine

    UMass Chan is supporting a collaboration among leaders in academic medicine to strengthen nutrition training in medical education.

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  • Record-breaking couples match multiplies Match Day 2026 excitement

    Record-breaking couples match multiplies Match Day 2026 excitement

    T.H. Chan School of Medicine students in the Class of 2026 celebrated successfully matching into their residency programs on March 20, including a record number of couples matches.    

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  • First year MD/PhD student Connor Lewis co-authors New England Journal of Medicine article

    First year MD/PhD student Connor Lewis co-authors New England Journal of Medicine article

    First year MD/PhD student Connor J. Lewis performed neuroimaging for the study on GM1 gangliosidosis.  

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  • UMass Chan’s 38th MLK tribute emphasizes acts of service to community

    UMass Chan’s 38th MLK tribute emphasizes acts of service to community

    The event featured the presentation of the inaugural Chancellor’s Award for Mission-Aligned Community Impact.

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  • Dean Flotte to receive Man of Good Conscience Award from American Medical Women’s Association

    Dean Flotte to receive Man of Good Conscience Award from American Medical Women’s Association

    Dean Flotte will be presented the Larry Zaroff Man of Good Conscience Award during the AMWA Awards Gala in March.  

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  • Top story: ‘A hope-filled moment’: UMass Chan celebrates Class of 2025

    Top story: ‘A hope-filled moment’: UMass Chan celebrates Class of 2025

    Top story: At the 52nd Commencement at UMass Chan on June 1, 265 degrees were presented.

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  • Top story: Catherine’s story: Tay-Sachs disease

    Top story: Catherine’s story: Tay-Sachs disease

    Top story: UMass Chan Medical School has launched Rare Diseases, Real Stories, a six-episode podcast series. This is Catherine's story. It is available on all major streaming platforms.

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  • Top story: Amid NIH funding cuts and uncertainty, Gov. Healey says future of science, research in Massachusetts is at stake

    Top story: Amid NIH funding cuts and uncertainty, Gov. Healey says future of science, research in Massachusetts is at stake

    Top story: The visit included a tour of the new Paul J. DiMare Center and a closed-door meeting with UMass Chan faculty members.

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