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About
About

Located at the University of Massachusetts Chan Medical School in Worcester, MA, the Department of Molecular, Cell & Cancer Biology is a collaborative group dedicated to translating fundamental discoveries in biomedical research into novel therapeutic strategies for cancer and other diseases.
Faculty
Faculty

Our faculty make innovative, high-impact discoveries in biomedical research in molecular, cell and cancer biology.
Research
Research

Explore how our bold discoveries are redefining our understanding of how diseases start and can be treated.
Bioinformatics Core
Bioinformatics Core

The MCCB Bioinformatics Core is a unique in-house resource that provides cutting-edge bioinformatics and biostatistics support to researchers in the department.
Education
Education

MCCB is dedicated to fostering innovation and training the next generation of scientists. Learn more about how MCCB equips students and early-career researchers with the skills and knowledge to drive scientific discovery.
- Postdoctoral Training
  
  Postdoctoral Training
  
  Educational Enrichment Activities
  
  Professional Development & Support
  
  MCCB Postdoc Achievements
- Graduate Training
  
  Graduate Programs
  
  Educational Enrichment Activities
  
  Professional Development & Support
  
  Current MCCB Students
  
  MCCB Student Achievements
  
  Michael R. Green, MD, PhD, Award in Graduate Research
  
  MCCB Faculty Awards in Education
Community & Culture
Community & Culture

MCCB values a supportive workplace environment where everyone feels valued and has fair access to resources and opportunities. Learn more about how we foster a positive culture that supports and empowers all members of the department to succeed.
Support Us
Support Us

Learn more about how you can support MCCB’s fundraising initiatives to advance research at UMass Chan.
- Michael R. Green, MD, PhD, Award in Graduate Research
- UMass Chan Cancer Research Team
MCCB SharePoint

Additional Resources

Ruscetti is one of 13 early-career scientists recognized for groundbreaking, visionary research accelerating progress toward new cancer treatments and cures.

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The all-day retreat brings together researchers studying diverse aspects of cancer biology and is a private event for the UMass Chan community.

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VIEW OPEN POSITIONS IN MCCB

The award recognizes outstanding graduate students at UMass Chan who have demonstrated research excellence.

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Conducting collaborative, cutting-edge research
to unravel molecular, cellular and genetic mechanisms of disease and translate our discoveries into innovative therapeutic strategies

Research

Explore how our bold discoveries are redefining our understanding of how diseases start and can be treated.

Education

Find out how MCCB equips students and early-career researchers with the skills and knowledge to drive scientific discovery.

Support

Learn more about how you can support MCCB’s fundraising initiatives to advance research at UMass Chan.

MCCB Recognitions & Achievements

Highlights from UMass Chan News

Getting Results…

UMass Chan Reverse Science Fair has Worcester high schoolers judging grad students, postdocs

The classic science fair format was flipped at UMass Chan as Worcester high school students judged research posters by graduate students and postdocs.

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More Highlights

Recent Publications

Huang et al. Adissp activates insulin-independent glucose disposal and energy expenditure in white fat to treat diabetes and cardiometabolic disease. Sci Adv, 2026. Article | Wang Lab
Tao et al. Dynamic S-acetylation of GSDMA regulates pyroptosis. ACS Chem Biol, 2026. Article | Mao Lab
Rai & Bergmann. AlphaFold3-based modeling uncovers the dynamic structural interface between full-length IAP antagonists and DIAP1 for apoptosis regulation in Drosophila. Cell Commun Signal, 2026. Article | Bergmann Lab
Lee et al. Interaction of IRS2 with PLK1 protects cells from mitotic stress. Cell Death Dis, 2026. Article | Shaw Lab
Winward et al. Epo and hypoxia accelerate a pattern of gradual cell cycle shortening in BFU-e and CFU-e erythroid progenitors in vivo. Blood Adv, 2026. Article | Socolovsky Lab

More Publications...

Grants, Honors & Awards

Getting Results…

Scot Wolfe Awarded ACS Grant for CRISPR Cancer Research

Scot Wolfe, PhD, is developing a CRISPR-Cas9 strategy to selectively destroy cancer cells driven by focal gene amplification.